RNA Details
Disease Name
kidney failure chronic
Tissue
kidney
RNA Symbol
mir-200c
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
qRT-PCR; Masson's trichrome staining etc.
Target
FASCIN-1;CD44
Pathway
NA
PubMed ID
Title
MiR-200b/c family inhibits renal fibrosis through modulating epithelial-to-mesenchymal transition via targeting fascin-1/CD44 axis
Year
2020
Function
Fascin-1 plays a critical role in renal fibrosis. miR-200b/c family could inhibit renal fibrosis through modulatingepithelial-mesenchymal transition (EMT) process by directly targeting fascin-1/cd45 axis.